Question 1

What routes can Cefiderocol be administered by?

Accepted Answer

Available routes: IV.

Question 2

Is Cefiderocol a controlled substance?

Accepted Answer

Cefiderocol is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Question 3

What are the warnings or contraindications for Cefiderocol?

Accepted Answer

Renal dose adjustment. Higher mortality in CR-Acinetobacter in one study. Reserve for MDR gram-negatives. No veterinary data.

Question 4

What are the side effects of Cefiderocol?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Cefiderocol: Renal dose adjustment. Higher mortality in CR-Acinetobacter in one study. Reserve for MDR gram-negatives. No veterinary data.

Question 5

How does Cefiderocol work?

Accepted Answer

Chelates iron to gain entry via bacterial iron transport systems (Trojan horse). Binds PBPs once inside. Stable against all classes of beta-lactamases.

Cefiderocol

Drug Class

Routes

Mechanism of Action

Side effects & warnings

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