ExoticRx · exoticrx.com/drugs/cefiderocol
US brand names:Fetroja
Chelates iron to gain entry via bacterial iron transport systems (Trojan horse). Binds PBPs once inside. Stable against all classes of beta-lactamases.
Renal dose adjustment. Higher mortality in CR-Acinetobacter in one study. Reserve for MDR gram-negatives. No veterinary data.
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