ExoticRx · exoticrx.com/drugs/cephapirin
Cefa-Lak, Cefa-Dri, ToDay, ToMorrow
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). First-generation cephalosporin with activity against gram-positive cocci and some gram-negative bacteria.
Cross-allergenicity with other beta-lactams possible. Adjust dose in renal impairment. Primarily used for bovine mastitis; limited companion animal data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IM | 10–30 mg/kg | q6-8h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
| Cat (Domestic) | IM | 10–30 mg/kg | q6-8h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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