Bird · Bubo virginianus · typical adult weight 0.90–1.80 kg
Chloramphenicol is dosed at 50 mg/kg IM q8h in great horned owls, per Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.651. Row as printed binds this dose to raptors on its own line: "Chloramphenicol Chloramphenicol Raptors IM 50 mg/kg tid Effective in flock treatment for Salmonella spp.". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. | SAFETY TEXT LOCATED 2026-08-20, Plumb's Veterinary Drug Handbook printed p.1380, verbatim: "Chloramphenicol may induce dose-dependent bone marrow suppression or idiosyncratic aplastic anemia […]" The low-risk clause is scoped to ophthalmic use in the source and is not carried over to these systemic rules. Comparator at printed p.555: "Florfenicol does not appear to have the same risk for aplastic anemia as chloramphenicol.". Chloramphenicol is used in great horned owls for Salmonella spp, See source. Routes documented in great horned owls: IM, IM, IV. A typical adult great horned owl weighs 0.90–1.80 kg. ExoticRx lists 2 cited dose rules for Chloramphenicol in great horned owls, drawn from published veterinary references. Verify against current literature before clinical use.
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 50 mg/kg | q8h | Salmonella spp | Moderate |
| Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.651. Row as printed binds this dose to raptors on its own line: "Chloramphenicol Chloramphenicol Raptors IM 50 mg/kg tid Effective in flock treatment for Salmonella spp.". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. | SAFETY TEXT LOCATED 2026-08-20, Plumb's Veterinary Drug Handbook printed p.1380, verbatim: "Chloramphenicol may induce dose-dependent bone marrow suppression or idiosyncratic aplastic anemia […]" The low-risk clause is scoped to ophthalmic use in the source and is not carried over to these systemic rules. Comparator at printed p.555: "Florfenicol does not appear to have the same risk for aplastic anemia as chloramphenicol." |
| IM, IV | 22 mg/kg | q3h | See source | Moderate | Avian Medicine: Principles and Application (Ritchie, Harrison & Harrison), p.811. Row as printed binds this dose to raptors on its own line: "Chloramphenicol 22 mg/kg IM, IV q3h Ducks (PD), raptors". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. | SAFETY TEXT LOCATED 2026-08-20, Plumb's Veterinary Drug Handbook printed p.1380, verbatim: "Chloramphenicol may induce dose-dependent bone marrow suppression or idiosyncratic aplastic anemia […]" The low-risk clause is scoped to ophthalmic use in the source and is not carried over to these systemic rules. Comparator at printed p.555: "Florfenicol does not appear to have the same risk for aplastic anemia as chloramphenicol." |
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These ranges are per kg. Enter your great horned owl's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Binds to 50S ribosomal subunit, inhibiting peptidyl transferase and bacterial protein synthesis. Bacteriostatic.
Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Species-specific contraindications and adverse-reaction reports for great horned owls may differ from canine / feline reference data — consult the primary citations listed with each rule.
Chloramphenicol dose ranges in great horned owls, with cited source references: IM 50 mg/kg q8h; IM, IV 22 mg/kg q3h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Chloramphenicol in great horned owls: IM, IM, IV.
Chloramphenicol is indicated in great horned owls for: Salmonella spp, See source.
These are general warnings for Chloramphenicol across species; consult the great horned owl dosing table above for species-specific guidance. Human health hazard: wear gloves when handling (aplastic anemia risk in humans). May cause bone marrow suppression in cats. Monitor CBC during prolonged use.
Why a species-specific page? Chloramphenicol pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in great horned owls — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.