Bird · Bubo virginianus · typical adult weight 0.90–1.80 kg
Cloxacillin is dosed at 250 mg/kg PO q12h in great horned owls, per Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.652. Row as printed binds this dose to raptors on its own line: "Cloxacillin Ampicox Syrup/ Raptors PO 250 mg/kg bid for 7-10 d Recommended in the treatment of infected". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity.. Cloxacillin is used in great horned owls for See source. Routes documented in great horned owls: PO. A typical adult great horned owl weighs 0.90–1.80 kg. ExoticRx lists 2 cited dose rules for Cloxacillin in great horned owls, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Orbenin, Dry-Clox
Contraindicated in Rabbit, Guinea Pig, Chinchilla, Hamster, Degu
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| PO | 250 mg/kg | q12h | See source | Moderate | Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.652. Row as printed binds this dose to raptors on its own line: "Cloxacillin Ampicox Syrup/ Raptors PO 250 mg/kg bid for 7-10 d Recommended in the treatment of infected". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. |
| PO | 100–250 mg/kg | q12-24h | See source | Moderate | Avian Medicine: Principles and Application (Ritchie, Harrison & Harrison), p.811. Row as printed binds this dose to raptors on its own line: "Cloxacillin 100-250 mg/kg PO, IM q12-24h Most species, including raptors; recommended for treating". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. |
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These ranges are per kg. Enter your great horned owl's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits bacterial cell wall synthesis by binding to PBPs. Resistant to staphylococcal penicillinase, providing targeted activity against penicillinase-producing Staphylococcus spp.
Cross-allergenicity with other beta-lactams. GI upset common with oral administration. Primarily used for staphylococcal mastitis in cattle.
Species-specific contraindications and adverse-reaction reports for great horned owls may differ from canine / feline reference data — consult the primary citations listed with each rule.
Cloxacillin dose ranges in great horned owls, with cited source references: PO 250 mg/kg q12h; PO 100–250 mg/kg q12-24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Cloxacillin in great horned owls: PO.
Cloxacillin is indicated in great horned owls for: See source.
These are general warnings for Cloxacillin across species; consult the great horned owl dosing table above for species-specific guidance. Cross-allergenicity with other beta-lactams. GI upset common with oral administration. Primarily used for staphylococcal mastitis in cattle.
Why a species-specific page? Cloxacillin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in great horned owls — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.