ExoticRx · exoticrx.com/drugs/cortisone-acetate
US brand names:Cortone
Cortisone Acetate is dosed at 0.5–1 mg/kg PO q12-24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed — Cortisone Acetate, Dosages/DOGS (corpus p.341, printed p.313-314) — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Inactive prodrug converted to cortisol (hydrocortisone) in the liver. Provides both glucocorticoid and mineralocorticoid activity for adrenal replacement.
Low potency glucocorticoid. Primarily used for adrenal insufficiency replacement. PU/PD, polyphagia at higher doses. Requires hepatic conversion.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1 mg/kg | q12-24h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed — Cortisone Acetate, Dosages/DOGS (corpus p.341, printed p.313-314) — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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