ExoticRx · exoticrx.com/drugs/danazol
US brand names:Danocrine
Danazol is dosed at 5–10 mg/kg PO q12h in dogs, per Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, Danazol, printed p.203, Indications and Clinical Uses: "Danazol (Danocrine) also has been used for treating refractory patients with immune-mediated […]"; same page, "When used to treat autoimmune disease, it is usually used in conjunction with other drugs (e.g., corticosteroids)."; Small Animal Dosage: "Dogs and Cats / 5-10 mg/kg q12h PO.". Verify against current literature before clinical use.
Synthetic androgen that suppresses FSH and LH. Used in veterinary medicine for immune-mediated hemolytic anemia (IMHA) and thrombocytopenia (ITP) as steroid-sparing agent.
Hepatotoxicity risk — monitor liver enzymes. Virilizing effects possible. Teratogenic. Used as adjunct to glucocorticoids in immune-mediated diseases.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5–10 mg/kg | q12h | Moderate | Papich MG, Saunders Handbook of Veterinary Drugs, 4th ed, Danazol, printed p.203, Indications and Clinical Uses: "Danazol (Danocrine) also has been used for treating refractory patients with immune-mediated […]"; same page, "When used to treat autoimmune disease, it is usually used in conjunction with other drugs (e.g., corticosteroids)."; Small Animal Dosage: "Dogs and Cats / 5-10 mg/kg q12h PO."Compilation only — we have not located an independent source that prints this figure. |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.