ExoticRx · exoticrx.com/drugs/danofloxacin
US brand names:Advocin, A180
Danofloxacin is dosed at 6 mg/kg IM See source in red-eared sliders, per Corum O, Corum DD, Altan F, et al. Pharmacokinetics of intravenous and intramuscular danofloxacin in red-eared slider turtles (Trachemys scripta elegans). J Vet Med Sci. 2019;81(5):753-757. PMID: 30853667; DOI: 10.1292/jvms.18-0609; PMCID: PMC6541859. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC6541859/. Verify against current literature before clinical use.
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication. Concentration-dependent bactericidal activity against gram-negative and some gram-positive organisms.
Avoid in growing animals (cartilage damage risk). Not for use in lactating dairy cattle. Injection site reactions possible. Avoid concurrent use with cation-containing products.
Species references:All Dog (Domestic) drugsAll Red-eared Slider drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 1.25–2.5 mg/kg | q24h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed; FDA openFDA Adverse Event Database |
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