ExoticRx · exoticrx.com/drugs/desmopressin-intranasal
US brand names:DDAVP Nasal Spray
Synthetic vasopressin analog (DDAVP) selective for V2 receptors. Promotes water reabsorption in collecting ducts. Applied to conjunctiva in small animals.
Conjunctival application in dogs/cats (drops into conjunctival sac). Used for central diabetes insipidus and von Willebrand disease testing. Water intoxication risk — monitor intake.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Apply to conjunctival sac (not nasal) | 1-4 drops conjunctival q12-24h | Strong | Valandro MA, de Pietro A, Martins DB. Diabetes Insipidus in a Dog. Acta Scientiae Veterinariae. 2013;41.; Nelson R. Polyuria, polydipsia, and diabetes insipidus. Paper presented at: Proceedings: World Small Animal Veterinary Assoc. World Congress 2002. PMID: 42428181 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.380 (2026-08-01). |
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