Cat · Felis catus · typical adult weight 2.50–7.00 kg
Donepezil is used in cat for Feline cognitive dysfunction. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Donepezil in cat, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Aricept
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.25–0.5 mg/kg | q24h | Long-term; reassess quarterly | Feline cognitive dysfunction | Anecdotal | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Reversible, non-competitive acetylcholinesterase inhibitor that increases acetylcholine concentrations at cholinergic synapses, improving cognitive function.
May cause GI upset, bradycardia, and muscle fasciculations. Monitor heart rate. Limited veterinary data — used investigationally for canine cognitive dysfunction.
Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Donepezil pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.