ExoticRx · exoticrx.com/drugs/echothiophate-iodide-ophthalmic
US brand names:Phospholine Iodide
Irreversible acetylcholinesterase inhibitor that produces prolonged miosis and increased aqueous outflow through the trabecular meshwork.
Long-acting — irreversible inhibition. Systemic cholinergic effects possible (bradycardia, GI hypermotility). Contraindicated with depolarizing neuromuscular blockers. Used for glaucoma refractory to other miotics.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Irreversible cholinesterase inhibitor — longest-acting miotic | 1 drop affected eye q12h-q24h | Moderate | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
| Dog (Domestic) | Ophthalmic | Rarely used diagnostic application | 1 drop each eye q24h for diagnostic trial | Weak | Gelatt KN, Veterinary Ophthalmology, 6th Ed |
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