Reptile · Terrapene carolina · typical adult weight 0.30–0.60 kg
Fluconazole is dosed at 21 mg/kg IV loading dose (single) in eastern box turtles, per Systemic Exophiala equina infection in an Eastern box turtle (Terrapene carolina carolina): a case report and literature review. Frontiers in Veterinary Science, 2023. DOI 10.3389/fvets.2023.1158393; PMID 37252397; PMCID PMC10213272. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10213272/. Fluconazole is used in eastern box turtles for Antifungal (systemic Exophiala equina infection). Routes documented in eastern box turtles: IV, PO. A typical adult eastern box turtle weighs 0.30–0.60 kg. ExoticRx lists 2 cited dose rules for Fluconazole in eastern box turtles, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Diflucan
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IV | 21 mg/kg | loading dose (single) | Antifungal (systemic Exophiala equina infection) | Anecdotal | Systemic Exophiala equina infection in an Eastern box turtle (Terrapene carolina carolina): a case report and literature review. Frontiers in Veterinary Science, 2023. DOI 10.3389/fvets.2023.1158393; PMID 37252397; PMCID PMC10213272. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10213272/ |
| PO | 5 mg/kg | SID for 30 days | Antifungal (systemic Exophiala equina infection) | Anecdotal | Systemic Exophiala equina infection in an Eastern box turtle (Terrapene carolina carolina): a case report and literature review. Frontiers in Veterinary Science, 2023. DOI 10.3389/fvets.2023.1158393; PMID 37252397; PMCID PMC10213272. URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC10213272/ |
Need the exact dose for your patient?
These ranges are per kg. Enter your eastern box turtle's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits fungal cytochrome P450 enzyme 14-alpha-demethylase, blocking ergosterol synthesis and disrupting fungal cell membrane.
Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Species-specific contraindications and adverse-reaction reports for eastern box turtles may differ from canine / feline reference data — consult the primary citations listed with each rule.
Fluconazole dose ranges in eastern box turtles, with cited source references: IV 21 mg/kg loading dose (single); PO 5 mg/kg SID for 30 days.
Documented routes for Fluconazole in eastern box turtles: IV, PO.
Fluconazole is indicated in eastern box turtles for: Antifungal (systemic Exophiala equina infection).
These are general warnings for Fluconazole across species; consult the eastern box turtle dosing table above for species-specific guidance. Hepatotoxic: monitor liver enzymes during prolonged therapy. Drug interactions via CYP450 inhibition. Good CNS and ocular penetration.
Why a species-specific page? Fluconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in eastern box turtles — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.