What is Fluralaner used for?

Fluralaner is indicated for: Caparinia tripilis mite infestation (capariniasis), Demodicosis, Flea and tick prevention, Generalised demodicosis (Demodex aurati and Demodex criceti), Psoroptes cuniculi (ear mite) treatment, Snake mite (Ophionyssus natricis) infestation.

Which species have cited Fluralaner dosing data?

Fluralaner dosing in the ExoticRx formulary covers 9 species: African Pygmy Hedgehog, Boa Constrictor, Cat (Domestic), Corn Snake, Dog (Domestic), Green Tree Python, Milk Snake, Rabbit (Domestic), Syrian Hamster.

Is Fluralaner a controlled substance?

Fluralaner is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Fluralaner

US brand names:Bravecto

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Fluralaner is dosed at 25 mg/kg PO once in rabbits, per Sheinberg G, Romero C, Heredia R, et al. Use of oral fluralaner for treatment of Psoroptes cuniculi in 15 naturally infected rabbits. Vet Derm. 2017;28(4):393-e91. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.850 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a). Verify against current literature before clinical use.

Drug Class

Antiparasitic

Routes

POTopical

Indications

Caparinia tripilis mite infestation (capariniasis)DemodicosisFlea and tick prevention

Mechanism of Action

Inhibits GABA and glutamate-gated chloride channels in arthropod nervous system. Highly selective for invertebrate receptors. 12-week duration.

Side effects & warnings

Seizure risk in animals with epilepsy history. Duration of action: 12 weeks (oral), 12 weeks (topical cats). Do not use in puppies <6 months or <2kg.

Evidence levels across 10 dose rules

Strong×2Moderate×5Anecdotal×3

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Sample dosing (2 of 10 cited rules)

A dog/cat sample is shown here. Cited dosing for all 9 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Cat (Domestic)	Topical	40–94 mg/kg	once q12 weeks	Strong	BRAVECTO - fluralaner topical solution for cats [US product label]. Madison, NJ: Intervet, Inc., a subsidiary of Merck & Company Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Plumb's 10th ed printed p.549, Fluralaner monograph spanning p.549-551.
Dog (Domestic)	PO	25–56 mg/kg	once q12 weeks	Strong	BRAVECTO - fluralaner tablet, chewable for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815; BRAVECTO - fluralaner topical solution for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. — Plumb's 10th ed printed p.549, Fluralaner monograph spanning p.549-551.

Backed by 7 published sourcesShow

· BRAVECTO - fluralaner tablet, chewable for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815; BRAVECTO - fluralaner topical solution for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Plumb's 10th ed printed p.549, Fluralaner monograph spanning p.549-551.
· BRAVECTO - fluralaner topical solution for cats [US product label]. Madison, NJ: Intervet, Inc., a subsidiary of Merck & Company Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Plumb's 10th ed printed p.549, Fluralaner monograph spanning p.549-551.
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Brosseau G. Oral fluralaner as a treatment for Demodex aurati and Demodex criceti in a golden (Syrian) hamster (Mesocricetus auratus). Can Vet J. 2020;61(2):135-137. PMID 32020929. https://pmc.ncbi.nlm.nih.gov/articles/PMC6973213/

· Cattarossi D, Marchiori E, Marcer F, Zorzi P, Frara E, De Benedictis GM. Single oral-dose fluralaner treatment against Ophionyssus natricis infestation - a large scale study demonstrating long-term efficacy in captive snakes. Parasitol Res. 2026;125(1):36. doi:10.1007/s00436-026-08657-7 https://europepmc.org/article/MED/41793465

· Romero C, Sheinberg Waisburd G, Pineda J, Heredia R, Yarto E, Cordero A. Fluralaner as a single dose oral treatment for Caparinia tripilis in a pygmy African hedgehog. Vet Dermatol. 2017;28(6):622. doi:10.1111/vde.12465. https://doi.org/10.1111/vde.12465

· Sheinberg G, Romero C, Heredia R, et al. Use of oral fluralaner for treatment of Psoroptes cuniculi in 15 naturally infected rabbits. Vet Derm. 2017;28(4):393-e91. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.850 doi:10.1111/vde.12429 — Carpenter's Exotic Animal Formulary 6th ed, Table 10.3 (Antiparasitic Agents Used in Rabbits.a).