What is Fluralaner used for?

Fluralaner is indicated for: Demodicosis, Flea and tick prevention.

Which species have cited Fluralaner dosing data?

Fluralaner dosing in the ExoticRx formulary covers 2 species: Cat (Domestic), Dog (Domestic).

Is Fluralaner a controlled substance?

Fluralaner is not federally scheduled in the US. Controlled-drug status differs by country — verify your local rules.

Fluralaner

US brand names:Bravecto

Calculate dosage

Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Fluralaner is dosed at 40–94 mg/kg Topical once q12 weeks in cats, per BRAVECTO - fluralaner topical solution for cats [US product label]. Madison, NJ: Intervet, Inc., a subsidiary of Merck & Company Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.578 (2026-08-01).. Verify against current literature before clinical use.

Drug Class

Antiparasitic

Routes

POTopical

Indications

DemodicosisFlea and tick prevention

Mechanism of Action

Inhibits GABA and glutamate-gated chloride channels in arthropod nervous system. Highly selective for invertebrate receptors. 12-week duration.

Side effects & warnings

Seizure risk in animals with epilepsy history. Duration of action: 12 weeks (oral), 12 weeks (topical cats). Do not use in puppies <6 months or <2kg.

Evidence levels across 3 dose rules

Moderate×1Strong×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by 2 published sources

· BRAVECTO - fluralaner tablet, chewable for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815; BRAVECTO - fluralaner topical solution for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.578 (2026-08-01).
· BRAVECTO - fluralaner topical solution for cats [US product label]. Madison, NJ: Intervet, Inc., a subsidiary of Merck & Company Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.578 (2026-08-01).

Sample dosing (2 of 3 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

Species	Route	Dose	Frequency	Evidence	Source
Cat (Domestic)	Topical	40–94 mg/kg	once q12 weeks	Strong	BRAVECTO - fluralaner topical solution for cats [US product label]. Madison, NJ: Intervet, Inc., a subsidiary of Merck & Company Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.578 (2026-08-01).
Dog (Domestic)	PO	25–56 mg/kg	once q12 weeks	Strong	BRAVECTO - fluralaner tablet, chewable for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fed84d87-049a-4e22-8091-451cde091815; BRAVECTO - fluralaner topical solution for dogs [US product label]. Madison, NJ: Merck Animal Health; 2019. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.578 (2026-08-01).

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