ExoticRx · exoticrx.com/drugs/fluvoxamine
US brand names:Luvox
Fluvoxamine is dosed at 1–2 mg/kg PO q24h in dogs, per Crowell-Davis SL, Murray TF, de Souza Dantas LM. Veterinary Psychopharmacology, 2nd Ed (Wiley, 2019), Table 8.1, printed p.105 (corpus p.133) - 'Fluvoxamine ... Dog 1-2 mg kg-1', with table note 'All doses given are orally, once daily, unless otherwise specified.' Corroborated by Plumb's Veterinary Drug Handbook 9th Ed, Fluvoxamine monograph, printed p.555 (corpus p.582): 'DOGS: Adjunctive treatment of behavioral disorders (extra-label): 1 - 2 mg/kg PO once daily.' — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Veterinary Psychopharmacology (Crowell-Davis) — ISBN 9781119226246, https://openlibrary.org/isbn/9781119226246. Verify against current literature before clinical use.
Selective serotonin reuptake inhibitor with sigma-1 receptor agonism. Increases serotonin availability in synaptic cleft.
Potent CYP1A2 and CYP2C19 inhibitor — significant drug interaction potential. May cause GI upset, sedation. Avoid with MAOIs. Taper to discontinue.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q24h | Weak | Crowell-Davis SL, Murray TF, de Souza Dantas LM. Veterinary Psychopharmacology, 2nd Ed (Wiley, 2019), Table 8.1, printed p.105 (corpus p.133) - 'Fluvoxamine ... Dog 1-2 mg kg-1', with table note 'All doses given are orally, once daily, unless otherwise specified.' Corroborated by Plumb's Veterinary Drug Handbook 9th Ed, Fluvoxamine monograph, printed p.555 (corpus p.582): 'DOGS: Adjunctive treatment of behavioral disorders (extra-label): 1 - 2 mg/kg PO once daily.' — EDITION NOTE 2026-08-06: this rule's Plumb's reference names the 9th edition, which is not held and was never consulted. The held copy is the 10th ed (2023). The Plumb's line was never confirmed against the held edition, so rely on it only as background; any other source named in this citation is unaffected. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207; Veterinary Psychopharmacology (Crowell-Davis) — ISBN 9781119226246, https://openlibrary.org/isbn/9781119226246 |
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