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Ganciclovir for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Ganciclovir is used in dog for CMV-like herpesvirus infections. Routes documented in dog: IV. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Ganciclovir in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Cytovene, Vitrasert

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV2.5–5 mg/kgq12h14-21 days induction, then maintenanceCMV-like herpesvirus infectionsWeakPlumb's Veterinary Drug Handbook, 9th Ed

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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Phosphorylated by viral kinase to triphosphate form which inhibits CMV DNA polymerase and incorporates into viral DNA causing chain termination.

Side effects & warnings

Myelosuppressive — monitor CBC. Teratogenic and carcinogenic. Handle with gloves. Renal dose adjustment required.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antiviral drugs with dog dosing

Ganciclovir dosing in other species

Why a species-specific page? Ganciclovir pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.