Cat · Felis catus · typical adult weight 2.50–7.00 kg
Glipizide is dosed at 2.5–5 mg per cat PO q12h in cats, per Reusch CE. Chapter 7: Feline Diabetes Mellitus. In: Feldman EC, Nelson RW, Reusch CE, Scott-Moncrieff JCR, eds. Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:258-314. doi:10.1016/b978-1-4557-4456-5.00007-9; Behrend E, Holford A, Lathan P, Rucinsky R, Schulman R. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. J Am Anim Hosp Assoc. 2018;54(1):1-21. doi:10.5326/jaaha-ms-6822 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.608 (2026-08-01).. Glipizide is used in cats for Diabetes mellitus (if insulin refused). Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Glipizide in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Glucotrol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 2.5–5 mg per catmax 5 mg total | q12h | Long-term; reassess every 2-4 weeks | Diabetes mellitus (if insulin refused) | Moderate | Reusch CE. Chapter 7: Feline Diabetes Mellitus. In: Feldman EC, Nelson RW, Reusch CE, Scott-Moncrieff JCR, eds. Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:258-314. doi:10.1016/b978-1-4557-4456-5.00007-9; Behrend E, Holford A, Lathan P, Rucinsky R, Schulman R. 2018 AAHA Diabetes Management Guidelines for Dogs and Cats. J Am Anim Hosp Assoc. 2018;54(1):1-21. doi:10.5326/jaaha-ms-6822 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.608 (2026-08-01). |
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Stimulates insulin secretion from functioning pancreatic beta cells by blocking ATP-sensitive potassium channels.
Cats only (dogs are primarily Type 1 DM). Requires functional beta cells. Hypoglycemia risk. Hepatotoxicity reported in cats. Not first-line (insulin preferred). May cause vomiting and hepatic lipidosis.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Glipizide dose range in cats, with cited source references: PO 2.5–5 mg per cat q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Glipizide in cats: PO.
Cited course lengths for Glipizide in cats include: Long-term; reassess every 2-4 weeks. Duration depends on the indication — match it to the specific dose rule in the table above.
Glipizide is indicated in cats for: Diabetes mellitus (if insulin refused).
These are general warnings for Glipizide across species; consult the cat dosing table above for species-specific guidance. Cats only (dogs are primarily Type 1 DM). Requires functional beta cells. Hypoglycemia risk. Hepatotoxicity reported in cats. Not first-line (insulin preferred). May cause vomiting and hepatic lipidosis.
Why a species-specific page? Glipizide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.