ExoticRx · exoticrx.com/drugs/ketamine-nasal
US brand names:Compounded Ketamine Nasal Spray
Ketamine Nasal is dosed at 14 mg/kg INTRANASAL Single dose; with midazolam 0.5 mg/kg IN in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.717, Ketamine monograph spanning p.717-724; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Ketamine monograph, printed p.717-724; the earlier note claiming no held source contained this figure was wrong and has been removed. — figure located 2026-08-05 at Plumb's 10th ed printed p.720, Ketamine monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
NMDA receptor antagonist absorbed via nasal mucosa. Provides sedation and chemical restraint without injection. Rapid absorption through nasal turbinates.
Controlled substance (CIII). Compounded formulation. Unpredictable absorption in some patients. May cause sneezing. Combine with midazolam intranasally for better effect.
Species references:All Cat (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | INTRANASAL | 14 mg/kg | Single dose; with midazolam 0.5 mg/kg IN | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.717, Ketamine monograph spanning p.717-724; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — located 2026-08-05 in Plumb's 10th ed, Ketamine monograph, printed p.717-724; the earlier note claiming no held source contained this figure was wrong and has been removed. — figure located 2026-08-05 at Plumb's 10th ed printed p.720, Ketamine monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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