ExoticRx · exoticrx.com/drugs/ketamine-nasal
US brand names:Compounded Ketamine Nasal Spray
Ketamine Nasal is dosed at 14 mg/kg INTRANASAL Single dose; with midazolam 0.5 mg/kg IN in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.717, Ketamine monograph spanning p.717-724. — Plumb's 10th ed, Ketamine monograph, printed p.717-724. — Plumb's 10th ed printed p.720, Ketamine monograph. Verify against current literature before clinical use.
NMDA receptor antagonist absorbed via nasal mucosa. Provides sedation and chemical restraint without injection. Rapid absorption through nasal turbinates.
Controlled substance (CIII). Compounded formulation. Unpredictable absorption in some patients. May cause sneezing. Combine with midazolam intranasally for better effect.
Species references:All Cat (Domestic) drugs
Controlled substance in the US
Controlled-drug status and schedules differ by country — check your local scheduling rules.
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | INTRANASAL | 14 mg/kg | Single dose; with midazolam 0.5 mg/kg IN | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023) — Plumb's 10th ed printed p.717, Ketamine monograph spanning p.717-724. — Plumb's 10th ed, Ketamine monograph, printed p.717-724. — Plumb's 10th ed printed p.720, Ketamine monograph.Compilation only — we have not located an independent source that prints this figure. |
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