Bird · Bubo virginianus · typical adult weight 0.90–1.80 kg
Ketoconazole is dosed at 25 mg/kg IM q12h in great horned owls, per Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.660. Row as printed binds this dose to raptors on its own line: "Ketoconazole Nizoral (Janssen) Raptors IM 25 mg/kg bid for 7 d Used for treatment of candidiasis […]". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity.. Ketoconazole is used in great horned owls for Used for treatment of candidiasis when other therapies have been. Routes documented in great horned owls: IM. A typical adult great horned owl weighs 0.90–1.80 kg. ExoticRx lists 1 cited dose rule for Ketoconazole in great horned owls, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Nizoral
| Route | Dose | Frequency | Indication | Evidence | Source |
|---|---|---|---|---|---|
| IM | 25 mg/kg | q12h | Used for treatment of candidiasis when other therapies have been | Moderate | Samour, Avian Medicine, 3rd Ed. (raptor formulary appendix), p.660. Row as printed binds this dose to raptors on its own line: "Ketoconazole Nizoral (Janssen) Raptors IM 25 mg/kg bid for 7 d Used for treatment of candidiasis […]". Located by line-level extraction and then read on the page; the species binding is the row's own species column, not text proximity. |
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These ranges are per kg. Enter your great horned owl's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits lanosterol 14-alpha-demethylase (CYP51), blocking ergosterol synthesis in fungal membranes. At high doses, inhibits adrenal and gonadal steroidogenesis.
Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Species-specific contraindications and adverse-reaction reports for great horned owls may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ketoconazole dose range in great horned owls, with cited source references: IM 25 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ketoconazole in great horned owls: IM.
Ketoconazole is indicated in great horned owls for: Used for treatment of candidiasis when other therapies have been.
These are general warnings for Ketoconazole across species; consult the great horned owl dosing table above for species-specific guidance. Hepatotoxic — monitor liver enzymes. Strong CYP inhibitor (many drug interactions). Requires gastric acid for absorption (do not give with antacids). Also used for Cushing's disease (adrenal steroidogenesis inhibition).
Why a species-specific page? Ketoconazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in great horned owls — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.