ExoticRx · exoticrx.com/drugs/labetalol
US brand names:Trandate, Normodyne
Labetalol is dosed at 0.2–0.5 mg/kg IV Slow IV bolus, repeat PRN q10-15min in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Non-selective beta-adrenergic and selective alpha-1 adrenergic antagonist, reducing heart rate, cardiac output, and peripheral vascular resistance.
May cause orthostatic hypotension, bradycardia. Hepatotoxicity reported rarely. Monitor heart rate and blood pressure.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.2–0.5 mg/kg | Slow IV bolus, repeat PRN q10-15min | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | IV | 0.1–0.25 mg/kg | Slow IV bolus PRN | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.