ExoticRx · exoticrx.com/drugs/leptospira-vaccine
US brand names:Nobivac Lepto4, Vanguard L4
Leptospira Vaccine is dosed at 1 dose SC Annually in dogs, per AAHA Canine Vaccination Guidelines 2022. Verify against current literature before clinical use.
Inactivated Leptospira serovars (canicola, grippotyphosa, icterohaemorrhagiae, pomona) stimulating active immunity and reducing shedding.
Higher anaphylaxis risk than other canine vaccines — especially in small breeds. Administer separately from other vaccines if possible. Annual boosters required.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.