Livestock · Ovis aries · typical adult weight 30.00–120.00 kg
Levamisole is dosed at 8–12 mg/kg PO Once in sheep, per US FDA. PROHIBIT (levamisole HCl) Soluble Drench Powder, ANADA 200-225, Huvepharma. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=baf0da35-573e-4abb-bdef-18870d5f5f72 - cattle and sheep; sheep 8 mg/kg single oral drench; sheep meat withdrawal 72 h; do not use in dairy animals of breeding age.. Levamisole is used in sheep for GI nematodes, GI nematodes, lungworms. Routes documented in sheep: PO. A typical adult sheep weighs 30.00–120.00 kg. ExoticRx lists 2 cited dose rules for Levamisole in sheep, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Levasole, Tramisol
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 8–12 mg/kg | Once | Single dose | GI nematodes | Strong | US FDA. PROHIBIT (levamisole HCl) Soluble Drench Powder, ANADA 200-225, Huvepharma. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=baf0da35-573e-4abb-bdef-18870d5f5f72 - cattle and sheep; sheep 8 mg/kg single oral drench; sheep meat withdrawal 72 h; do not use in dairy animals of breeding age. |
| PO | 8 mg/kg | single dose | — | GI nematodes, lungworms | Strong | LEVAMED SOLUBLE DRENCH POWDER - Levamisole Hydrochloride Powder [US Product Label for Cattle and Sheep]. Bimeda, Inc.; 2019. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a5cd77e0-af84-4ef6-b0bf-b3dc706352c3 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.772 (2026-08-01). |
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These ranges are per kg. Enter your sheep's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Nicotinic acetylcholine receptor agonist causing sustained muscle contraction and paralysis in nematodes. Also has immunostimulant properties.
Narrow safety margin — toxicity causes cholinergic signs (salivation, tremors, dyspnea). TOXIC to dogs at high doses. Immunomodulatory use at low doses.
Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.
Levamisole dose ranges in sheep, with cited source references: PO 8–12 mg/kg Once; PO 8 mg/kg single dose. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Levamisole in sheep: PO.
Cited course lengths for Levamisole in sheep include: Single dose. Duration depends on the indication — match it to the specific dose rule in the table above.
Levamisole is indicated in sheep for: GI nematodes, GI nematodes, lungworms.
These are general warnings for Levamisole across species; consult the sheep dosing table above for species-specific guidance. Narrow safety margin — toxicity causes cholinergic signs (salivation, tremors, dyspnea). TOXIC to dogs at high doses. Immunomodulatory use at low doses.
Why a species-specific page? Levamisole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.