ExoticRx · exoticrx.com/drugs/methocarbamol-compounded-oral
US brand names:Compounded Methocarbamol
Methocarbamol Compounded Oral is dosed at 22–44 mg/kg PO q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 10th ed, Methocarbamol monograph, corpus PDF p.882. DOGS/CATS (label dosage, FDA-approved): Injectable - "For relief of moderate conditions: 44 mg/kg IV initial dose"; "For controlling severe effects of strychnine and tetanus: 55 - 220 mg/kg IV initial dose... The […]" Oral (tablets) - "132 mg/kg PO on Day 1 in 2 or 3 equally divided doses (ie, every 8 to 12 hours), then 66 - 132 […]" DOGS, intervertebral disk disease (extra-label): "Anecdotal dosages of 15 - 20 mg/kg PO every 8 hours are usually noted." HORSES (label dosage, FDA-approved): "For moderate conditions: 4.4 - 22 mg/kg IV to effect"; "For severe conditions (tetanus): 22 - 55 mg/kg IV". — RETRIEVED FINDING - CHANGE REQUIRED (retrieved 2026-08-19): Dogs and Cats: 44 mg/kg q8h PO or IV on the first day, and then 22-44 mg/kg q8h PO. — Papich 4th ed (2016), printed p.509 / corpus p.537; corroborated "Dogs, Cats: 20-45 mg/kg p.o. q8h." — BSAVA Small Animal Formulary 10th ed Part A, printed p.257 / corpus p.273 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "22 mg/kg IV to effect1 * Ga6ape,(-,: Concurrent use may result in resp" — which resolves in the monograph's own reference list to: ROBAXIN-V INJECTABLE - Methocarbamol Liquid (Solution) [US Product Label for Dogs, Cats, and Horses]. Kinetic Technologies, LLC; 2017. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose.. Verify against current literature before clinical use.
Centrally acting muscle relaxant that depresses polysynaptic reflexes. Exact mechanism unknown but likely involves carbamic acid ester CNS depression.
Compounded for easier dosing in small animals. Sedation and weakness at higher doses. Do not combine with other CNS depressants. Available commercially as tablets/injection.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 22–44 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 10th ed, Methocarbamol monograph, corpus PDF p.882. DOGS/CATS (label dosage, FDA-approved): Injectable - "For relief of moderate conditions: 44 mg/kg IV initial dose"; "For controlling severe effects of strychnine and tetanus: 55 - 220 mg/kg IV initial dose... The […]" Oral (tablets) - "132 mg/kg PO on Day 1 in 2 or 3 equally divided doses (ie, every 8 to 12 hours), then 66 - 132 […]" DOGS, intervertebral disk disease (extra-label): "Anecdotal dosages of 15 - 20 mg/kg PO every 8 hours are usually noted." HORSES (label dosage, FDA-approved): "For moderate conditions: 4.4 - 22 mg/kg IV to effect"; "For severe conditions (tetanus): 22 - 55 mg/kg IV". — RETRIEVED FINDING - CHANGE REQUIRED (retrieved 2026-08-19): Dogs and Cats: 44 mg/kg q8h PO or IV on the first day, and then 22-44 mg/kg q8h PO. — Papich 4th ed (2016), printed p.509 / corpus p.537; corroborated "Dogs, Cats: 20-45 mg/kg p.o. q8h." — BSAVA Small Animal Formulary 10th ed Part A, printed p.257 / corpus p.273 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "22 mg/kg IV to effect1 * Ga6ape,(-,: Concurrent use may result in resp" — which resolves in the monograph's own reference list to: ROBAXIN-V INJECTABLE - Methocarbamol Liquid (Solution) [US Product Label for Dogs, Cats, and Horses]. Kinetic Technologies, LLC; 2017. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |
| Cat (Domestic) |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| PO |
| 22–44 mg/kg |
| q8-12h |
| Weak |
| Plumb's Veterinary Drug Handbook, 10th ed, Methocarbamol monograph, corpus PDF p.882. DOGS/CATS (label dosage, FDA-approved): Injectable - "For relief of moderate conditions: 44 mg/kg IV initial dose"; "For controlling severe effects of strychnine and tetanus: 55 - 220 mg/kg IV initial dose... The […]" Oral (tablets) - "132 mg/kg PO on Day 1 in 2 or 3 equally divided doses (ie, every 8 to 12 hours), then 66 - 132 […]" DOGS, intervertebral disk disease (extra-label): "Anecdotal dosages of 15 - 20 mg/kg PO every 8 hours are usually noted." HORSES (label dosage, FDA-approved): "For moderate conditions: 4.4 - 22 mg/kg IV to effect"; "For severe conditions (tetanus): 22 - 55 mg/kg IV". — RETRIEVED FINDING - CHANGE REQUIRED (retrieved 2026-08-19): Dogs and Cats: 44 mg/kg q8h PO or IV on the first day, and then 22-44 mg/kg q8h PO. Up to 130 mg/kg for severe conditions. — Papich, Saunders Handbook of Veterinary Drugs, held 4th ed (2016), printed p.509 / corpus p.537 | ORIGINAL SOURCE THE BOOK CITES (2026-08-20): the dose row carries superscript 1 — "22 mg/kg IV to effect1 * Ga6ape,(-,: Concurrent use may result in resp" — which resolves in the monograph's own reference list to: ROBAXIN-V INJECTABLE - Methocarbamol Liquid (Solution) [US Product Label for Dogs, Cats, and Horses]. Kinetic Technologies, LLC; 2017. This records what the handbook attributes the figure to. It is NOT a statement that the reference was read or that it validates the dose. |