ExoticRx · exoticrx.com/drugs/omeprazole-compounded-suspension
US brand names:Compounded Omeprazole
Omeprazole Compounded Suspension is dosed at 1–2 mg/kg PO q12-24h in dogs, per Bersenas AM, Mathews KA, Allen DG, Conlon PD. Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs. Am J Vet Res. 2005;66(3):425-431. / 3. Tolbert K, Bissett S, King A, et al. Efficacy of oral famotidine and 2 omeprazole formulations for the control of intragastric pH in dogs. J Vet Intern Med. 2011;25(1):47-54. doi:10.2460/ajvr.2005.66.425 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.981 (2026-08-01). — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Verify against current literature before clinical use.
Irreversibly inhibits H+/K+ ATPase (proton pump) in gastric parietal cells, blocking the final step of acid production. Compounded for small animal dosing convenience.
Stability of compounded formulations varies — verify with pharmacist. Enteric coating destroyed in suspension (compensate with higher dose or bicarbonate buffer). Use within BUD.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–2 mg/kg | q12-24h | Moderate | Bersenas AM, Mathews KA, Allen DG, Conlon PD. Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs. Am J Vet Res. 2005;66(3):425-431. / 3. Tolbert K, Bissett S, King A, et al. Efficacy of oral famotidine and 2 omeprazole formulations for the control of intragastric pH in dogs. J Vet Intern Med. 2011;25(1):47-54. doi:10.2460/ajvr.2005.66.425 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.981 (2026-08-01). — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| Cat (Domestic) | PO | 1–1.5 mg/kg | q12h |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.
| Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — figure located 2026-08-05 at Plumb's 10th ed printed p.955, Omeprazole monograph; the page cited previously does not carry it. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |