ExoticRx · exoticrx.com/drugs/omeprazole
US brand names:Prilosec, GastroGard
Omeprazole is dosed at 1 mg/kg PO q12h in ferrets, per Hoefer HL, et al. Gastrointestinal diseases of ferrets. In: Quesenberry KE, OrcuttCJ, Mans C, et al. Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery, 4th ed., Elsevier, St. Louis, MO; 2021:27-38. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.957 doi:10.1016/b978-0-323-48435-0.00003-4 — Carpenter's Exotic Animal Formulary 6th ed, Table 11.10 (Miscellaneous Agents Used in Ferrets.a). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929; Ferrets, Rabbits, and Rodents: Clinical Medicine and Surgery — ISBN 9780323484350, https://openlibrary.org/isbn/9780323484350. Verify against current literature before clinical use.
Irreversibly inhibits H+/K+-ATPase (proton pump) on parietal cells, providing potent and prolonged gastric acid suppression.
Must not be crushed (enteric-coated). Takes 3-5 days for full effect. Long-term use may affect calcium/magnesium absorption. Interacts with drugs requiring acid pH for absorption.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugsAll Ferret drugsAll Rabbit (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 4 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.5–1.5 mg/kg | q12-24h | Strong | Bersenas AM, Mathews KA, Allen DG and Conlon PD (2005) Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs. American Journal of Veterinary Research 66, 425-431 — Verified against BSAVA Small Animal Formulary, 10th Ed, Part A, p.308 (2026-08-01). — LOCATOR CONVENTION 2026-08-07: the bare 'p.308' in this citation is the PDF index of the held scan, not the printed page. The PRINTED page is p.292; verified by finding the drug named there. If you are holding the book, turn to p.292. — SOURCE EDITION: BSAVA Small Animal Formulary, Part A — Canine and Feline — ISBN 9781910443705, https://openlibrary.org/isbn/9781910443705 |
| Dog (Domestic) | PO | 1–1.5 mg/kg | q12h | Strong | Marks SL. Chapter 273: Diseases of the Pharynx and Esophagus. In: Ettinger SJ, Feldman EC, Cote E, eds. Textbook of Veterinary Internal Medicine. Vol 2. Elsevier Health Sciences; 2017:1476-1490. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.982 (2026-08-01). — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.