Cat · Felis catus · typical adult weight 2.50–7.00 kg
Omeprazole is dosed at 0.5–1 mg/kg PO q24h in cats, per Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207. Omeprazole is used in cats for Gastric ulceration, severe gastritis, GI ulcer management/prevention. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 2 cited dose rules for Omeprazole in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Prilosec, GastroGard
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.5–1 mg/kg | q24h | 14-28 days | Gastric ulceration, severe gastritis | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
| PO | 0.5–1 mg/kg | q12h | 7-14 days | GI ulcer management/prevention | Moderate | Plumb's Veterinary Drug Handbook, 10th ed (2023, held copy; the original seed cited the 9th, which was never consulted) — Plumb's 10th ed (held) printed p.953, Omeprazole monograph spanning p.953-955; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 0.75–1 | PO | BSAVA Small Animal Formulary, 10th ed — Part A (Canine and Feline)p.308 | 0.75-1 mg/kg p.o. q24h for a maximum of 8 weeks. |
| 1–2 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.607 | • 20 mg per dog q24h PO or 1-2 mg/kg • 1 mg/kg q24h PO. |
| 1 | PO | Papich Saunders Handbook of Veterinary Drugs, 4th edp.607 | • 20 mg per dog q24h PO or 1-2 mg/kg • 1 mg/kg q24h PO. |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Irreversibly inhibits H+/K+-ATPase (proton pump) on parietal cells, providing potent and prolonged gastric acid suppression.
Must not be crushed (enteric-coated). Takes 3-5 days for full effect. Long-term use may affect calcium/magnesium absorption. Interacts with drugs requiring acid pH for absorption.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Omeprazole dose ranges in cats, with cited source references: PO 0.5–1 mg/kg q24h; PO 0.5–1 mg/kg q12h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Omeprazole in cats: PO.
Cited course lengths for Omeprazole in cats include: 14-28 days; 7-14 days. Duration depends on the indication — match it to the specific dose rule in the table above.
Omeprazole is indicated in cats for: Gastric ulceration, severe gastritis, GI ulcer management/prevention.
These are general warnings for Omeprazole across species; consult the cat dosing table above for species-specific guidance. Must not be crushed (enteric-coated). Takes 3-5 days for full effect. Long-term use may affect calcium/magnesium absorption. Interacts with drugs requiring acid pH for absorption.
Why a species-specific page? Omeprazole pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.