ExoticRx · exoticrx.com/drugs/metolazone
US brand names:Zaroxolyn
Quinazoline diuretic that inhibits sodium reabsorption in the distal convoluted tubule. Retains efficacy in renal impairment unlike true thiazides.
Potent diuretic synergy with loop diuretics — severe electrolyte depletion. Monitor potassium, sodium, magnesium. Used for furosemide-resistant CHF.
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