Cat · Felis catus · typical adult weight 2.50–7.00 kg
Metolazone is dosed at 0.1–0.4 mg/kg PO q24h in cats, per Plumb's Veterinary Drug Handbook, 9th Ed. Metolazone is used in cats for Refractory congestive heart failure. Routes documented in cats: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Metolazone in cats, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Zaroxolyn
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 0.1–0.4 mg/kg | q24h | Short-term pulses; close monitoring | Refractory congestive heart failure | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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These ranges are per kg. Enter your cat's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Quinazoline diuretic that inhibits sodium reabsorption in the distal convoluted tubule. Retains efficacy in renal impairment unlike true thiazides.
Potent diuretic synergy with loop diuretics — severe electrolyte depletion. Monitor potassium, sodium, magnesium. Used for furosemide-resistant CHF.
Species-specific contraindications and adverse-reaction reports for cats may differ from canine / feline reference data — consult the primary citations listed with each rule.
Metolazone dose range in cats, with cited source references: PO 0.1–0.4 mg/kg q24h. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Metolazone in cats: PO.
Cited course lengths for Metolazone in cats include: Short-term pulses; close monitoring. Duration depends on the indication — match it to the specific dose rule in the table above.
Metolazone is indicated in cats for: Refractory congestive heart failure.
These are general warnings for Metolazone across species; consult the cat dosing table above for species-specific guidance. Potent diuretic synergy with loop diuretics — severe electrolyte depletion. Monitor potassium, sodium, magnesium. Used for furosemide-resistant CHF.
Why a species-specific page? Metolazone pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cats — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.