ExoticRx · exoticrx.com/drugs/nalidixic-acid
NegGram
First-generation quinolone inhibiting DNA gyrase. Active only against gram-negative urinary pathogens. Achieves therapeutic levels only in urine.
Largely superseded by fluoroquinolones. Resistance develops rapidly. CNS effects possible. Not effective systemically.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 5.5–11 mg/kg | q8h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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