Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg
Niacinamide is used in dog for Discoid lupus erythematosus / pemphigus foliaceus, Sebaceous adenitis. Routes documented in dog: PO. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 2 cited dose rules for Niacinamide in dog, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Nicotinamide
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 250–500 mg/kg | q8h (flat dose per dog based on weight) | Chronic use; reassess at 8 weeks | Discoid lupus erythematosus / pemphigus foliaceus | Moderate | Miller WH, Small Animal Dermatology, 7th Ed |
| PO | 250–500 mg/kg | q8h (flat dose) | Long-term use | Sebaceous adenitis | Weak | Miller WH, Small Animal Dermatology, 7th Ed |
Absolute dose ceiling, regardless of body weight: 500 mg total (PO).
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These ranges are per kg. Enter your dog's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Inhibits phosphodiesterase, reducing inflammatory mediator release from mast cells and neutrophils. Blocks antigen-induced lymphocyte transformation.
GI upset possible. Often combined with tetracycline/doxycycline for immune-mediated skin diseases (pemphigus, discoid lupus). Generally well-tolerated.
Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.
Why a species-specific page? Niacinamide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.