ExoticRx · exoticrx.com/drugs/nintedanib
US brand names:Ofev
Triple angiokinase inhibitor blocking VEGFR, FGFR, and PDGFR tyrosine kinases, reducing fibroblast migration, proliferation, and extracellular matrix deposition.
Diarrhea most common side effect. Hepatotoxicity risk — monitor LFTs. Bleeding risk. Investigational for pulmonary fibrosis in dogs.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.