ExoticRx · exoticrx.com/drugs/nitric-oxide-inhaled
US brand names:INOmax
Endogenous vasodilator that activates guanylate cyclase in pulmonary vascular smooth muscle, producing cGMP and selective pulmonary vasodilation.
Requires specialized delivery system and monitoring (methemoglobin, NO2). Rebound pulmonary hypertension with abrupt discontinuation. ICU setting only.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | INHALATION | ICU only | Continuous inhalation in ICU | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | INHALATION | Very limited feline data | Continuous inhalation | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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