ExoticRx · exoticrx.com/drugs/penciclovir-topical
US brand names:Denavir
Activated by viral thymidine kinase. Triphosphate form inhibits viral DNA polymerase. Longer intracellular half-life than acyclovir.
Topical use only. For FHV-1 dermatitis in cats. Minimal systemic absorption. Apply with gloves. Limited veterinary evidence.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Cat (Domestic) | TOPICAL | 1% cream applied to herpetic skin lesions | q2h during waking hours | Weak | Papich Handbook of Veterinary Drugs, 5th Ed |
| Dog (Domestic) | TOPICAL | Very rare indication in dogs | q2h during waking hours | Extrapolated | Papich Handbook of Veterinary Drugs, 5th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.