Penicillin G for Sheep
Livestock · Ovis aries · typical adult weight 30.00–120.00 kg
Penicillin G is used in sheep for Bacterial infections, foot rot, blackleg. Routes documented in sheep: IM. A typical adult sheep weighs 30.00–120.00 kg. ExoticRx lists 1 cited dose rule for Penicillin G in sheep, drawn from published veterinary references. Verify against current literature before clinical use.
Trade names: Pen-G, Crysticillin
Dose ranges
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| IM | 3.96–13.2 mg/kg | q24h | 3-5 days | Bacterial infections, foot rot, blackleg | Moderate | Plumb's Veterinary Drug Handbook |
Need the exact dose for your patient?
These ranges are per kg. Enter your sheep's weight to get the precise dose and draw-up volume — unit and concentration math done for you.
Mechanism of action
Inhibits bacterial cell wall synthesis by binding PBPs. Bactericidal. Narrow spectrum: primarily gram-positive and some anaerobes.
Side effects & warnings
CONTRAINDICATED in rabbits, guinea pigs, hamsters. Hypersensitivity reactions. Procaine form: IM/SC only (never IV). Potassium form: slow IV only. Pain at injection site.
Species-specific contraindications and adverse-reaction reports for sheep may differ from canine / feline reference data — consult the primary citations listed with each rule.
Other Antibiotic drugs with sheep dosing
Penicillin G dosing in other species
Why a species-specific page? Penicillin G pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in sheep — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.