Question 1

What is Penicillin G used for?

Accepted Answer

Penicillin G is indicated for: Bacterial infections, blackleg, foot rot, Gram-positive infections, leptospirosis (procaine), listeriosis, Susceptible infections.

Question 2

What routes can Penicillin G be administered by?

Accepted Answer

Available routes: IM, IV, SC.

Question 3

Which species have cited Penicillin G dosing data?

Accepted Answer

Penicillin G dosing in the ExoticRx formulary covers 5 species: African Grey Parrot, Cat (Domestic), Dog (Domestic), Goat (Caprine), Sheep (Ovine).

Question 4

Is Penicillin G a controlled substance?

Accepted Answer

Penicillin G is not federally scheduled as a controlled substance, but is veterinary prescription only in most jurisdictions.

Question 5

What are the warnings or contraindications for Penicillin G?

Accepted Answer

CONTRAINDICATED in rabbits, guinea pigs, hamsters. Hypersensitivity reactions. Procaine form: IM/SC only (never IV). Potassium form: slow IV only. Pain at injection site.

Question 6

What are the side effects of Penicillin G?

Accepted Answer

Reported side effects, adverse reactions, and contraindications for Penicillin G: CONTRAINDICATED in rabbits, guinea pigs, hamsters. Hypersensitivity reactions. Procaine form: IM/SC only (never IV). Potassium form: slow IV only. Pain at injection site.

Question 7

How does Penicillin G work?

Accepted Answer

Inhibits bacterial cell wall synthesis by binding PBPs. Bactericidal. Narrow spectrum: primarily gram-positive and some anaerobes.

Species	Route	Dose	Frequency	Evidence	Source
Dog (Domestic)	IM	13.2–26.4 mg/kg	q12-24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed
Cat (Domestic)	IM	13.2–26.4 mg/kg	q12-24h	Strong	Plumb's Veterinary Drug Handbook, 9th Ed

Penicillin G

Drug Class

Routes

Indications

Mechanism of Action

Side effects & warnings

Species with Penicillin G dosing data (5 dose rules)

Evidence levels across 5 dose rules

Backed by 4 published sources

Sample dosing (2 of 5 cited rules)

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