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Polyethylene Glycol 3350 (PEG) for Cat

Cat · Felis catus · typical adult weight 2.50–7.00 kg

Polyethylene Glycol 3350 (PEG) is used in cat for Constipation/Megacolon. Routes documented in cat: PO. A typical adult cat weighs 2.50–7.00 kg. ExoticRx lists 1 cited dose rule for Polyethylene Glycol 3350 (PEG) in cat, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: MiraLAX, GoLYTELY

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
PO10–25 mg/kgq12-24hLong-term; titrate to effect; may combine with cisaprideConstipation/MegacolonModeratePlumb's Veterinary Drug Handbook, 9th Ed; JFMS Constipation Review

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Mechanism of action

High molecular weight polymer that is osmotically active but not absorbed, retaining water in the intestinal lumen and softening stool.

Side effects & warnings

Safe for chronic constipation. May cause bloating and flatulence initially. Ensure adequate hydration. Well tolerated in cats and dogs.

Species-specific contraindications and adverse-reaction reports for cat may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Miscellaneous drugs with cat dosing

Polyethylene Glycol 3350 (PEG) dosing in other species

Why a species-specific page? Polyethylene Glycol 3350 (PEG) pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in cat — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.