Reptile · Python regius · typical adult weight 1.00–2.00 kg
Ponazuril is dosed at 30 mg/kg PO q48h for two doses in ball pythons, per Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed (2019), antiparasitic table: "Ponazuril / All reptiles / 30 mg/kg PO q 48 h for two doses / Empirical". Ponazuril is used in ball pythons for Cryptosporidiosis. Routes documented in ball pythons: PO. A typical adult ball python weighs 1.00–2.00 kg. ExoticRx lists 1 cited dose rule for Ponazuril in ball pythons, drawn from published veterinary references. Verify against current literature before clinical use.
US trade names: Marquis
| Route | Dose | Frequency | Duration | Indication | Evidence | Source |
|---|---|---|---|---|---|---|
| PO | 30 mg/kg | q48h for two doses | Ongoing; poor response in many reptiles | Cryptosporidiosis | Weak | Mader's Reptile and Amphibian Medicine and Surgery, 3rd ed (2019), antiparasitic table: "Ponazuril / All reptiles / 30 mg/kg PO q 48 h for two doses / Empirical".Compilation only — we have not located an independent source that prints this figure. |
Every held source for this drug and species, as printed. Where they differ, both are shown — the choice is yours, not ours.
| Dose (mg/kg) | Route | Source | As printed |
|---|---|---|---|
| 30 | PO | Mader's Reptile and Amphibian Medicine and Surgery, 3rd edTable 128.3 | 30 mg/kg PO q12h × 3 days, repeat in 3 wk; often more effective at 30 mg/kg PO q24h × 30 days; may work with less frequent treatments52 Coccidia but not Cryptosporidium; may have s |
Figures are transcribed from the cited page or table of each held edition and are shown for reference only. They are not dose recommendations, they do not feed the calculator, and none has been reviewed by a veterinarian.
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Inhibits coccidian parasite mitochondrial electron transport, disrupting energy production. Active metabolite of toltrazuril.
Marketed for horses (EPM); used off-label in other species. Palatability may be poor. Compounded suspensions should be verified for stability.
Species-specific contraindications and adverse-reaction reports for ball pythons may differ from canine / feline reference data — consult the primary citations listed with each rule.
Ponazuril dose range in ball pythons, with cited source references: PO 30 mg/kg q48h for two doses. Reference ranges from cited sources — verify against current literature before clinical use.
Documented routes for Ponazuril in ball pythons: PO.
Cited course lengths for Ponazuril in ball pythons include: Ongoing; poor response in many reptiles. Duration depends on the indication — match it to the specific dose rule in the table above.
Ponazuril is indicated in ball pythons for: Cryptosporidiosis.
These are general warnings for Ponazuril across species; consult the ball python dosing table above for species-specific guidance. Marketed for horses (EPM); used off-label in other species. Palatability may be poor. Compounded suspensions should be verified for stability.
Why a species-specific page? Ponazuril pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in ball pythons — the rules above are the citations specific to this species, not generic recommendations.
Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.