ExoticRx · exoticrx.com/drugs/roflumilast
US brand names:Daliresp
Roflumilast is dosed at 0.1–0.5 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Selective PDE4 inhibitor reducing inflammatory cell activation and mediator release. Anti-inflammatory effect on airway inflammation.
Novel anti-inflammatory for chronic airway disease. GI upset (nausea, diarrhea) common. Weight loss. Psychiatric effects in humans — monitor behavior. Very limited vet data.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.1–0.5 mg/kg | q24h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.