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Roxithromycin

Rulid

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Sourced from published veterinary references. Awaiting credentialed clinical reviewer — our editorial process.

Drug Class

Antibiotic

Routes

PO

Indications

RespiratoryRespiratory infectionssoft tissue infections

Mechanism of Action

Binds 50S ribosomal subunit inhibiting protein synthesis. Macrolide with improved acid stability and longer half-life than erythromycin.

Side effects & warnings

GI upset less than erythromycin. QTc prolongation possible. CYP3A4 interactions. Not available in US.

Species with Roxithromycin dosing data (2 dose rules)

Cat (Domestic)Dog (Domestic)

Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs

Evidence levels across 2 dose rules

Weak×2

Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.

Backed by a published source

  • · Plumb's Veterinary Drug Handbook, 9th Ed

Sample dosing (2 of 2 cited rules)

A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.

SpeciesRouteDoseFrequencyEvidenceSource
Cat (Domestic)PO5–10 mg/kgq12-24hWeakPlumb's Veterinary Drug Handbook, 9th Ed
Dog (Domestic)PO5–10 mg/kgq12-24hWeakPlumb's Veterinary Drug Handbook, 9th Ed

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