ExoticRx · exoticrx.com/drugs/sarolaner
US brand names:Simparica
Sarolaner is dosed at 2 mg/kg PO once in african pygmy hedgehogs, per 3. Antelo J, Núñez C, Contreras L, et al. Use of sarolaner in African hedgehogs (Atelerix albiventris) infested with Caparinia tripilis. J Exot Pet Med. 2020;35:1-3. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.738 doi:10.1053/j.jepm.2020.06.001 — Carpenter's Exotic Animal Formulary 6th ed, Table 8.3 (Antiparasitic Agents Used in Hedgehogs). The copy held is an ebook conversion with no printed page numbers, so the table — not the page — is the citable location. — SOURCE EDITION: Carpenter's Exotic Animal Formulary — ISBN 9780323833929, https://openlibrary.org/isbn/9780323833929. Verify against current literature before clinical use.
Potent isoxazoline that inhibits GABA and glutamate-gated chloride channels in arthropod nervous system. Monthly flea, tick, and mite protection.
Seizure potential in dogs with neurologic history. Not for use in puppies <6 months. Effective against Demodex and Sarcoptes mites.
Species references:All African Pygmy Hedgehog drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 2–4 mg/kg | q30 days | Moderate | Becskei C, Cuppens O, Mahabir SP. Efficacy and safety of sarolaner in the treatment of canine ear mite infestation caused by Otodectes cynotis: a non-inferiority study. Vet Dermatol. 2018;29(2):100-e39. / 23. Six RH, Becskei C, Mazaleski MM, et al. Efficacy of sarolaner, a novel oral isoxazoline, against two common mite infestations in dogs: Demodex spp. and Otodectes cynotis. Veterinary Parasitology. 2016;222:62-66. / 2. Becskei C, Cuppens O, Mahabir SP. Efficacy and safety of sarolaner against generalized demodicosis in dogs in European countries: a non-inferiority study. Vet Dermatol. 2018;29(3):203-e72. doi:10.1111/vde.12521 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1173 (2026-08-01). — Plumb's 10th ed (held) printed p.1144, Sarolaner monograph spanning p.1144-1146; page located 2026-08-05 from the book's own running heads, verified to name the drug in its body text. — SOURCE EDITION: Plumb's Veterinary Drug Handbook — ISBN 9781394172207, https://openlibrary.org/isbn/9781394172207 |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.