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Semaglutide for Dog

Dog · Canis lupus familiaris · typical adult weight 2.00–80.00 kg

Semaglutide is used in dog for Obesity (investigational). Routes documented in dog: SC. A typical adult dog weighs 2.00–80.00 kg. ExoticRx lists 1 cited dose rule for Semaglutide in dog, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Ozempic, Wegovy

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
SC0.01–0.05 mg/kgq7 daysPer protocolObesity (investigational)ExtrapolatedPapich Handbook of Veterinary Drugs, 5th Ed

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Mechanism of action

Long-acting GLP-1 receptor agonist with weekly dosing. Enhances insulin secretion, suppresses glucagon, and reduces appetite/body weight.

Side effects & warnings

Investigational in veterinary medicine. Weekly injection. GI upset (nausea, vomiting) expected. Pancreatitis risk. Very limited veterinary data — off-label research use.

Species-specific contraindications and adverse-reaction reports for dog may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Endocrine drugs with dog dosing

Semaglutide dosing in other species

Why a species-specific page? Semaglutide pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in dog — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.