ExoticRx · exoticrx.com/drugs/solithromycin
US brand names:CEM-101
Solithromycin is dosed at 5–10 mg/kg PO q24h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Binds 50S ribosomal subunit at three sites (vs. two for older macrolides). Overcomes macrolide resistance. Bacteriostatic.
Hepatotoxicity risk. QTc minimal. GI upset less than erythromycin. No veterinary data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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