ExoticRx · exoticrx.com/drugs/somatostatin
US brand names:Octreotide(Sandostatin)
Somatostatin is dosed at 10–40 mcg/dog SC q8-12h in dogs, per Nelson R. Beta-Cell Neoplasia: Insulinoma. In: Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:348-375. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.978 (2026-08-01).. Verify against current literature before clinical use.
Synthetic somatostatin analog inhibiting growth hormone, insulin, glucagon, and gastrin release. Reduces splanchnic blood flow.
Used for insulinoma (suppresses insulin secretion), GI bleeding, and acromegaly. GI upset, injection site pain. Gallbladder sludge/stones with chronic use.
Species references:All Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | SC | 10–40 mcg/dog | q8-12h | Moderate | Nelson R. Beta-Cell Neoplasia: Insulinoma. In: Canine and Feline Endocrinology. 4th ed. Elsevier Saunders; 2015:348-375. — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.978 (2026-08-01). |
Upgrade to Pro or Student to unlock the full dose ranges and frequency for every species. The drug's mechanism, warnings, indications, and cited sources are free to read.
View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.