ExoticRx · exoticrx.com/drugs/succinylcholine
US brand names:Anectine, Quelicin
Also known as: Suxamethonium
Succinylcholine is dosed at 0.3 mg/kg IV Single dose in dogs, per Keegan RD. Chapter 14: Muscle Relaxants and Neuromuscular Blockade. In: Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA, eds. Veterinary Anesthesia and Analgesia, The 5th Edition of Lumb and Jones. 5th ed. Wiley Blackwell; 2015:260-276. doi:10.1002/9781119421375.ch14 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1215 (2026-08-01).. Verify against current literature before clinical use.
Depolarizing neuromuscular blocking agent that mimics acetylcholine at the motor end plate, causing initial fasciculations followed by sustained depolarization and paralysis.
Ultra-short acting. Requires mechanical ventilation during effect. Malignant hyperthermia risk. Hyperkalemia risk (especially with rhabdomyolysis, denervation). No reversal agent. Store refrigerated.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | IV | 0.3 mg/kg | Single dose | Moderate | Keegan RD. Chapter 14: Muscle Relaxants and Neuromuscular Blockade. In: Grimm KA, Lamont LA, Tranquilli WJ, Greene SA, Robertson SA, eds. Veterinary Anesthesia and Analgesia, The 5th Edition of Lumb and Jones. 5th ed. Wiley Blackwell; 2015:260-276. doi:10.1002/9781119421375.ch14 — Verified against Plumb's Veterinary Drug Handbook, 10th Ed, p.1215 (2026-08-01). |
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