ExoticRx · exoticrx.com/drugs/tecovirimat
US brand names:TPOXX
Tecovirimat is dosed at 10–20 mg/kg PO q12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Inhibits the VP37 protein required for release of enveloped virions from infected cells. Active against orthopoxviruses (smallpox, monkeypox, cowpox).
Strategic national stockpile drug. Headache, nausea common. Potential veterinary use for cowpox/parapox in exotic species. Limited data.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
Each ExoticRx dose rule is graded by the strength of its primary evidence — see the editorial process.
A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.