ExoticRx · exoticrx.com/drugs/zafirlukast
US brand names:Accolate
Competitive CysLT1 receptor antagonist blocking leukotriene D4 and E4 effects. Reduces bronchoconstriction and airway inflammation.
Give on empty stomach (food reduces absorption by 40%). Hepatotoxicity rare but monitor liver enzymes. CYP2C9 inhibitor — drug interactions. Limited vet data.
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