ExoticRx · exoticrx.com/drugs/zafirlukast
Accolate
Competitive CysLT1 receptor antagonist blocking leukotriene D4 and E4 effects. Reduces bronchoconstriction and airway inflammation.
Give on empty stomach (food reduces absorption by 40%). Hepatotoxicity rare but monitor liver enzymes. CYP2C9 inhibitor — drug interactions. Limited vet data.
Species references:All Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 1 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 1–5 mg/kg | q12h | Weak | Plumb's Veterinary Drug Handbook, 9th Ed |
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