ExoticRx · exoticrx.com/drugs/zileuton
US brand names:Zyflo
Inhibits 5-lipoxygenase enzyme, blocking synthesis of leukotrienes (LTB4, LTC4, LTD4, LTE4) from arachidonic acid, reducing airway inflammation.
Hepatotoxicity risk — monitor ALT. Multiple daily dosing needed. Limited veterinary data. Theoretical benefit in feline asthma.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.