ExoticRx · exoticrx.com/drugs/bimatoprost
US brand names:Lumigan
Bimatoprost is dosed at Solution: Initially, 1 drop to the affected eye(s) once daily in the evening; increase to twice daily as glaucoma progresses in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed, Bimatoprost, p.1376 (Dosages). Underlying in-species primary source is ref 3, Gelatt & MacKay, 'Effect of different dose schedules of bimatoprost on intraocular pressure and pupil size in the glaucomatous Beagle', J Ocul Pharmacol Ther 2002;18:525-534.. Verify against current literature before clinical use.
Prostaglandin F2-alpha analog increasing uveoscleral outflow of aqueous humor. Reduces intraocular pressure.
Used for glaucoma. May cause miosis, conjunctival hyperemia, and iris pigmentation changes. Potential for anterior uveitis in dogs — use with caution.
Species references:All Dog (Domestic) drugs
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| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | Ophthalmic | Solution: Initially, 1 drop to the affected eye(s) once daily in the evening; increase to twice daily as glaucoma progresses | q12-24h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed, Bimatoprost, p.1376 (Dosages). Underlying in-species primary source is ref 3, Gelatt & MacKay, 'Effect of different dose schedules of bimatoprost on intraocular pressure and pupil size in the glaucomatous Beagle', J Ocul Pharmacol Ther 2002;18:525-534. |
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