ExoticRx · exoticrx.com/drugs/carvedilol
US brand names:Coreg
Carvedilol is dosed at 2–30 mg/kg PO q24h in pet rats, per Meredith A. BSAVA Small Animal Formulary: Part B: Exotic Pets, British Small Animal Veterinary Association, Quedgeley, Gloucester, UK; 2015. — Source: Carpenter's Exotic Animal Formulary, 6th Ed, p.794 — Carpenter's Exotic Animal Formulary 6th ed, Table 9.5 (Cardiovascular Agents Used in Rodents). Verify against current literature before clinical use.
Non-selective beta-adrenergic blocker with alpha-1 blocking and antioxidant properties. Reduces heart rate, blood pressure, and cardiac remodeling.
Start at low dose and titrate slowly. Bradycardia, hypotension, worsening heart failure initially. Do not abruptly discontinue. Give with food.
Species references:All African Grey Parrot drugsAll Dog (Domestic) drugsAll Dwarf Hamster drugsAll Green-cheeked Conure drugsAll Pet Rat drugsAll Syrian Hamster drugs
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A dog/cat sample is shown here. Cited dosing for all 6 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.05–0.3 mg/kg | q12h | Moderate | Marcondes-Santos M, Tarasoutchi F, Mansur AP, Strunz CM. Effects of carvedilol treatment in dogs with chronic mitral valvular disease. J Vet Intern Med. 2007;21(5):996-1001. doi:10.1111/j.1939-1676.2007.tb03055.x; Marcondes-Santos M, Mansur AP, Fragata FS, Strunz CM. Short-term follow-up of exercise training program and beta-blocker treatment on quality of life in dogs with naturally acquired chronic mitral valve disease. Braz J Med Biol Res. 2015;48(10):886-894. doi:10.1590/1414-431x20154568 — Plumb's 10th ed printed p.193, Carvedilol monograph spanning p.193-194. |
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