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Cefazolin for Guinea Pig

Pocket Pet · Cavia porcellus · typical adult weight 0.70–1.20 kg

Cefazolin is used in guinea pig for Surgical prophylaxis. Routes documented in guinea pig: IV. A typical adult guinea pig weighs 0.70–1.20 kg. ExoticRx lists 1 cited dose rule for Cefazolin in guinea pig, drawn from published veterinary references. Verify against current literature before clinical use.

Trade names: Ancef, Kefzol

Dose ranges

RouteDoseFrequencyDurationIndicationEvidenceSource
IV20–25 mg/kgq2h intraoperativeSingle doseSurgical prophylaxisModerateCarpenter's Exotic Animal Formulary, 6th Ed

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These ranges are per kg. Enter your guinea pig's weight to get the precise dose and draw-up volume — unit and concentration math done for you.

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Mechanism of action

Inhibits bacterial cell wall synthesis. First-generation cephalosporin with excellent gram-positive coverage. Commonly used for surgical prophylaxis.

Side effects & warnings

Perioperative use common. Adjust dose in renal impairment. Pain at IM injection site.

Species-specific contraindications and adverse-reaction reports for guinea pig may differ from canine / feline reference data — consult the primary citations listed with each rule.

Other Antibiotic drugs with guinea pig dosing

Cefazolin dosing in other species

Why a species-specific page? Cefazolin pharmacokinetics differ across species: dose ranges, intervals, and route preferences are not interchangeable. Cross-extrapolation from canine doses is unsafe in guinea pig — the rules above are the citations specific to this species, not generic recommendations.

Sourced from published veterinary references; awaiting credentialed clinical reviewer. See our editorial process. Reference only — not veterinary advice.