ExoticRx · exoticrx.com/drugs/ciclopirox
US brand names:Loprox, Penlac
Chelates polyvalent metal cations (Fe3+, Al3+) inhibiting metal-dependent enzymes. Disrupts mitochondrial electron transport and nutrient uptake.
Topical use only. Contact dermatitis possible. Nail lacquer requires prolonged use. Broad activity including dermatophytes, yeasts, and some bacteria.
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.