ExoticRx · exoticrx.com/drugs/clonidine
US brand names:Catapres
Clonidine is dosed at 0.01–0.05 mg/kg PO q8-12h in dogs, per Plumb's Veterinary Drug Handbook, 9th Ed. Verify against current literature before clinical use.
Stimulates central alpha-2 adrenergic receptors, reducing sympathetic outflow, heart rate, and blood pressure.
Abrupt discontinuation can cause rebound hypertension. Sedation common. Use cautiously with other CNS depressants.
Species references:All Cat (Domestic) drugsAll Dog (Domestic) drugs
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A dog/cat sample is shown here. Cited dosing for all 2 species — reptiles, birds, pocket pets, livestock, and equine — is free on the per-species pages above. Pro adds the weight-based calculator for every species.
| Species | Route | Dose | Frequency | Evidence | Source |
|---|---|---|---|---|---|
| Dog (Domestic) | PO | 0.01–0.05 mg/kg | q8-12h | Moderate | Plumb's Veterinary Drug Handbook, 9th Ed |
| Cat (Domestic) | PO | 0.005–0.02 mg/kg | q12h | Extrapolated | Plumb's Veterinary Drug Handbook, 9th Ed |
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View PlansSource citations and evidence levels available on the live page. Reference only — verify against current literature before clinical use.